| 產(chǎn)品編號(hào) | bs-1225R-BF488 |
| 英文名稱 | Rabbit Anti-Adenosine A3 Receptor/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的腺苷受體A3抗體 |
| 別 名 | adenosine A3 receptor; A3AR; AD 026; AD026; ADORA 3; ADORA3; bA552M11.5; RP11 552M11.7; TGPCR1; adenosine receptor A3 isoform 1; adenosine receptor A3 isoform 2; AA3R_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 心血管 神經(jīng)生物學(xué) 細(xì)胞膜受體 G蛋白偶聯(lián)受體 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Rat, (predicted: Mouse, Dog, Pig, Cow, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | Flow-Cyt=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 35kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ADORA3 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Function: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction. Subcellular Location: Cell membrane. Post-translational modifications: Phosphorylation on Ser-317 may be crucial for rapid desensitization. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 140 Human Omim: 600445 Human SwissProt: P33765 Human SwissProt: Q6P2N6 Human Unigene: 281342 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. ADORA-3(腺苷受體A3)屬于G蛋白偶聯(lián)受體家族，在腺苷調(diào)節(jié)細(xì)胞活力和生長(zhǎng)中起關(guān)鍵作用，并且在很多腫瘤中表達(dá)增高，A3AR可能成為腫瘤診斷標(biāo)志物和治療靶點(diǎn)。 |
