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Rabbit Anti-ORP8/BF594 Conjugated antibody (bs-6334R-BF594)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6334R-BF594
英文名稱 Rabbit Anti-ORP8/BF594 Conjugated antibody
中文名稱 BF594標記的氧化固醇結合蛋白8抗體
別    名 MST120; MSTP120; ORP 8; OSBP related protein 8; OSBP10; OSBPL8; Oxysterol binding protein like 8; Oxysterol binding protein like protein 8; Oxysterol binding protein related protein 8; OSBL8_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 心血管  細胞生物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 101kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ORP8
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
ORP8 is a member of the oxysterol-binding protein related protein family. In humans, the gene family consists of 12 members, and extensive splice variation increases the number of encoded protein products substantially. The ORPs have been implicated as sterol sensors that regulate a number of cellular functions including sterol and neutral lipid metabolism, intracellular lipid transport, membrane trafficking and cell signaling. ORP8 has been recently shown to act as a sterol sensor that affects the reverse cholesterol transport process via modulation of ABCA1 expression and macrophage cholesterol efflux.

Subcellular Location:
Endoplasmic reticulum

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the OSBP family.
Contains 1 PH domain.

Database links:

Entrez Gene: 114882 Human

Entrez Gene: 237542 Mouse

Omim: 606736 Human

SwissProt: Q9BZF1 Human

SwissProt: B9EJ86 Mouse

Unigene: 220204 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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