日日操日日操,亚洲日本午夜激情,人妻内射精品一区二区,国产一区北条麻妃

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产白丝内射,va在线蛋播,欧美日韩,国产在线。观看
Rabbit Anti-PPAR Gamma/HRP Conjugated antibody (bs-4590R-HRP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-4590R-HRP
英文名稱 Rabbit Anti-PPAR Gamma/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標(biāo)記的過氧化酶活化增生受體γ抗體
別    名 CIMT1; HUMPPARG; NR1C3; Nuclear receptor subfamily 1 group C member 3; PAX8/PPARG Fusion Gene; Peroxisome Proliferator Activated Receptor gamma; PPAR gamma; PPARG; PPARG1; PPARG2; PPARG3; CIMT1; GLM1; HUMPPARG; NR1C3; Nuclear receptor subfamily 1 group C member 3; PAX8/PPARG Fusion Gene; Peroxisome proliferator activated nuclear receptor gamma variant 1; Peroxisome proliferator activated receptor gamma 1; Peroxisome Proliferator Activated Receptor gamma; Peroxisome proliferator-activated receptor gamma; PPAR gamma; PPAR-gamma; PPARG; PPARG_HUMAN; PPARG1; PPARG2; PPARG3; PPAR gamma 1; PPAR gamma 2; PPAR gamma 3; PPAR gamma-1; PPAR gamma-2; PPAR gamma-3.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PPAR Gamma
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The PPAR gamma antibody mainly is exist in the white fat organization, the fat for the PPAR gamma is born, blood sugar stability, the disease respond, the artery gruel kind hardens to rise the important function with the tumor occurrence of etc. all, but concerning the PPAR gamma to bone of function is a new research heat to order in recent years.A PPAR of many researches report gamma was go together with the body is after activate can the function promote many capable cells divided to increase to living but repress the ossification cell to divide to cause the bone measure the decrease or bone softs toward the fat cell in the marrow, the PPAR gamma promotes the ability and bones that the fat cell divide metabolize closely related, the performance is increasing along with the growth marrow fat content of the age, the ossification cell metabolism the outcome reduce, the different construction PPAR gamma 2 have the important function.

Function:
Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis.

Subunit:
Forms a heterodimer with the retinoic acid receptor RXRA called adipocyte-specific transcription factor ARF6. Interacts with NCOA6 coactivator, leading to a strong increase in transcription of target genes. Interacts with coactivator PPARBP, leading to a mild increase in transcription of target genes. Interacts with FAM120B. Interacts with PRDM16 (By similarity). Interacts with NOCA7 in a ligand-inducible manner. Interacts with NCOA1 LXXLL motifs. Interacts with TGFB1I1. Interacts with DNTTIP2. Interacts with PRMT2.

Subcellular Location:
Nucleus.

Tissue Specificity:
Highest expression in adipose tissue. Lower in skeletal muscle, spleen, heart and liver. Also detectable in placenta, lung and ovary.

DISEASE:
Note=Defects in PPARG can lead to type 2 insulin-resistant diabetes and hyptertension. PPARG mutations may be associated with colon cancer.
Defects in PPARG may be associated with susceptibility to obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
Defects in PPARG are the cause of familial partial lipodystrophy type 3 (FPLD3) [MIM:604367]. Familial partial lipodystrophies (FPLD) are a heterogeneous group of genetic disorders characterized by marked loss of subcutaneous (sc) fat from the extremities. Affected individuals show an increased preponderance of insulin resistance, diabetes mellitus and dyslipidemia.
Genetic variations in PPARG can be associated with susceptibility to glioma type 1 (GLM1) [MIM:137800]. Gliomas are central nervous system neoplasms derived from glial cells and comprise astrocytomas, glioblastoma multiforme, oligodendrogliomas, and ependymomas. Note=Polymorphic PPARG alleles have been found to be significantly over-represented among a cohort of American patients with sporadic glioblastoma multiforme suggesting a possible contribution to disease susceptibility.

Similarity:
Belongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain.

Database links:

Entrez Gene: 5468 Human

Entrez Gene: 19016 Mouse

Entrez Gene: 25664 Rat

SwissProt: P37231 Human

SwissProt: P37238 Mouse

SwissProt: O88275 Rat

Unigene: 162646 Human

Unigene: 3020 Mouse

Unigene: 23443 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

過氧化物酶體增殖物激活受體γ(PPARγ)主要存在于白色脂肪組織,PPARγ對(duì)于脂肪生成、血糖穩(wěn)定、炎癥反應(yīng)、動(dòng)脈粥樣硬化和腫瘤等的發(fā)生都起到重要的作用。主要在脂肪細(xì)胞內(nèi)表達(dá)。PPARγ是噻唑烷二酮類藥物(TZDs)作用的藥靶,又是脂肪細(xì)胞分化的重要調(diào)節(jié)因子。經(jīng)研究發(fā)現(xiàn),PPARγ在肥胖及胰島素抵抗的發(fā)病機(jī)制中具有十分重要的意義,是治療糖尿病、肥胖等代謝性疾病的重要藥靶。 過氧化物酶體增殖物激活受體γ(PPARγ)屬Ⅱ型核受體超家族成員,主要在脂肪細(xì)胞內(nèi)表達(dá)。PPARγ是噻唑烷二酮類藥物(TZDs)作用的藥靶,又是脂肪細(xì)胞分化的重要調(diào)節(jié)因子?,F(xiàn)有研究(包括一次于美國(guó)加州大學(xué)進(jìn)行的研究)發(fā)現(xiàn)PPARγ在肥胖及胰島素抵抗的發(fā)病機(jī)制中具有十分重要的意義,是治療糖尿病、肥胖等代謝性疾病的重要藥靶。目前,該受體蛋白質(zhì)水平的篩選模式已經(jīng)建立,并正在建立該受體的報(bào)告基因的細(xì)胞水平篩選評(píng)價(jià)模式。
版權(quán)所有 2004-2026 m.bklrv.cn 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
熟妇视频在线播放| 亚洲成人操爱操爱操爱| 2022亚洲丝袜中文字幕| 人人操欧美风骚| 操大骚逼逼逼网| 91无码在线观看区一区二| 日韩乱伦欧美| 日本A√一区二区三区| 少妇入屄网| 久久久久久久久久久免费视频| 欧美特黄一级大色片| 大鸡巴欧美大鸡巴| 国产欧美日韩成人看片| 99更新国产精品一区二区三区| 91国产区在线| 美女被男人桶免费国产| 久久婷婷欧美国产精品| 欧美黑人久久久| 亚洲九九视频| 狠狠色在线视频| 国产久久理论片| 草草电影院免费看| 午夜影院三级黄色| 1人精品一区二区三区色0| 欧洲丝袜熟女乱| 操亚洲丰满的女人视频| 亚洲成人手机AV| 天天攃天天爽天天日天天添天天攃| av加勒比在线一区二区| 日本天天日天天澡天天干| 欧美日韩限制| 成人91网站午夜视频| 大鸡巴性交免费| 午夜嘿嘿二三区| 日本精品黄色片| 久久久久毛片免费欢看| 特一黄色网AV在线| 国产鸡吧视频免费| 欧美制服熟女久久| 亚洲伊人五月天久久久| 艹在线观看日韩一区|