日日操日日操,亚洲日本午夜激情,人妻内射精品一区二区,国产一区北条麻妃

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产成人激情AV在线,日本一卡二卡在线观看免费
Rabbit Anti-TIMP-2/PE-Cy7 Conjugated antibody (bs-0416R-PE-Cy7)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-0416R-PE-Cy7
英文名稱 Rabbit Anti-TIMP-2/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標(biāo)記的金屬蛋白酶組織抑制因子-2抗體
別    名 Metalloproteinase inhibitor 2 precursor; Tissue inhibitor of metalloproteinases 2; Collagenase inhibitor; CSC 21K; CSC21K; TIMP2; TIMP 2; TIMP 2; TIMP metallopeptidase inhibitor 2; TIMP2_HUMAN; Metalloproteinase inhibitor 2; CSC-21K; TIMP-2.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 腫瘤  心血管  細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  生長(zhǎng)因子和激素  合成與降解  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TIMP-2 (125-160aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008].

Function:
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.

Subunit:
Interacts (via the C-terminal) with MMP2 (via the C-terminal PEX domain); the interaction inhibits the MMP2 activity.

Subcellular Location:
Secreted.

Post-translational modifications:
The activity of TIMP2 is dependent on the presence of disulfide bonds.

Similarity:
Belongs to the protease inhibitor I35 (TIMP) family.
Contains 1 NTR domain.

Database links:

Entrez Gene: 282093 Cow

Entrez Gene: 100135629 Guinea pig

Entrez Gene: 7077 Human

Entrez Gene: 21858 Mouse

Entrez Gene: 100008689 Rabbit

Entrez Gene: 29543 Rat

Omim: 188825 Human

SwissProt: P16368 Cow

SwissProt: Q9WUC6 Guinea pig

SwissProt: P16035 Human

SwissProt: P25785 Mouse

SwissProt: Q9TRZ7 Rabbit

SwissProt: P30121 Rat

Unigene: 633514 Human

Unigene: 206505 Mouse

Unigene: 10161 Rat




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

合成與降解(Synthesis and Degradation)
TIMP-2與TIMP-1一樣是基質(zhì)金屬蛋白酶的抑制酶,其功能與MMP相反,能抑制腫瘤細(xì)胞的浸潤(rùn)和轉(zhuǎn)移,主要用于各種惡性腫瘤如乳腺癌等的研究。TIMP-2又稱為CSC-21K,是一種21-24kDa的糖蛋白,在多種組織細(xì)胞中表達(dá),它可以和MMPs家族成員以共價(jià)鍵方式形成復(fù)合物,從而發(fā)揮其抑制作用。在正常生理?xiàng)l件下,MMPs和TIMPs之間的平衡狀態(tài)是維持細(xì)胞外基質(zhì)正常狀態(tài)所必需的,一旦它們之間的比例失調(diào),就會(huì)造成一系列的病理狀態(tài)。
版權(quán)所有 2004-2026 m.bklrv.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
首页4k岛国视频一区二区| 干人妻激情偷拍视频| 日韩免费激情午夜福利一区二区| 嗯啊嗯操我好爽视频| 黑人无码二区| 中文字幕99页久久久| 日本免费不卡一二三区在线视频| 日精品一区二区| 午夜免费黄色电影网站| 欧美成人综合色区文化在线| 欧美一区国产日韩一区二区| 91不卡手机在线视频| 超碰人人摸人人爽| 日本 丰满熟妇| 久久三极片| 成人网站在线进入爽爽爽| 啪啪啪一区二区啊啊啊受不了| 午夜福利av在线的| 大香蕉视频观看伊人在线| 久久久亚洲 av| 一区二区三区爽爽爽| 松下凛凛子av一区二区三区| 欧美精选一区二区三区三州| 人妻av色色中文字幕| 亚洲五码黄片| 在线 国产 欧美| AⅤ观看导航网站| 久久综合日本性爱| 色五月激情阁| 插bb 视频| 亚洲大骚逼视频| 国产精品鲁鲁吧在线观看视频| 麻豆小电影| 欧美操逼大吊美女| 日韩亚洲欧美亚洲在线| 欧美成人嘿嘿在线观看| 91丝袜后入| 色片婷婷基地| 精油按摩少妇日韩一区二区三区| 免费作爱视频| 欧美一区二区三区精|