日日操日日操,亚洲日本午夜激情,人妻内射精品一区二区,国产一区北条麻妃

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
偷拍少妇久久久久久久,流水真人wwwwwwwwww,超级97碰一二三区
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-LRSAM1/HRP Conjugated antibody (bs-9387R-HRP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-9387R-HRP
英文名稱 Rabbit Anti-LRSAM1/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標記的LRSAM1蛋白抗體
別    名 E3 ubiquitin protein ligase LRSAM1; hTAL; Leucine rich repeat and sterile alpha motif containing protein 1; RIFLE; TAL; Tsg101 associated ligase; LRSM1_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導(dǎo)  細胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 84kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LRSAM1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
LRSAM1 is an E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivation of the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos. It selectively regulates cell adhesion molecules and plays a role in receptor endocytosis and viral budding. LRSAM1 contains a RING-type zinc finger, 5 leucine-rich repeats and 1 SAM (sterile alpha motif) domain. The coiled coil domains interact with the SB domain of TSG101. The PTAP motifs mediate the binding to UEV domains. There are 3 isoforms produced by alternative splicing.

Function:
E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos.

Subunit:
Interacts with TSG101.

Subcellular Location:
Cytoplasm. Note=Displays a punctuate distribution and localizes to a submembranal ring.

Tissue Specificity:
Highly expressed in adult spinal cord motoneurons as well as in fetal spinal cord and muscle tissue.

DISEASE:
Defects in LRSAM1 are a cause of Charcot-Marie-Tooth disease type 2P (CMT2P) [MIM:614436]. CMT2P is an axonal form of Charcot-Marie-Tooth disease, a disorder of the peripheral nervous system, characterized by progressive weakness and atrophy, initially of the peroneal muscles and later of the distal muscles of the arms. Charcot-Marie-Tooth disease is classified in two main groups on the basis of electrophysiologic properties and histopathology: primary peripheral demyelinating neuropathies (designated CMT1 when they are dominantly inherited) and primary peripheral axonal neuropathies (CMT2). Neuropathies of the CMT2 group are characterized by signs of axonal degeneration in the absence of obvious myelin alterations, normal or slightly reduced nerve conduction velocities, and progressive distal muscle weakness and atrophy. Nerve conduction velocities are normal or slightly reduced.

Similarity:
Contains 6 LRR (leucine-rich) repeats.
Contains 1 RING-type zinc finger.
Contains 1 SAM (sterile alpha motif) domain.

Database links:

Entrez Gene: 90678 Human

Omim: 610933 Human

SwissProt: Q6UWE0 Human

Unigene: 495188 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 m.bklrv.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
日b免费视频观看| 8x8x国产精品一区二区三区| 女人午夜免费小视频| 国产黄色久av| 美日韩不卡1区2区在线| 97高清色频| 亚洲人妻在线丰满尤物内射喷水| 久久久免费看片网站| 自拍另类欧美视频| 欧美v国产久久久| 国产全黄色片| 五月成人黄色| 欧美精品一区二区啪啪拍| 自拍偷拍av色| 操笔视频呜呜啊啊啊啊| 久久漂亮人妻被中出中文字幕| 国产精品久久久91蜜臀网站| 黄色三级片成人99精品| 鸡巴日逼内射视频| 欧美狂野日骚逼| 东京久久夜夜操伊人久久| 操逼网站国产一级精品| 老鸭窝无码视频| 粉嫩无码小穴久久久久久久久久| 久久久久久久久久j| yy6080久久伦理一区二区| 麻豆射频一区二区三区| www.三级片欧美.com| 久久激情五月婷线观看视频 | 日本新版内射人妻一区二区三区视频 | 无码一区二区三区四区不卡精品 | 国产欧美日韩综合在线搜索 | 国产精品久久久幺幺幺幺幺幺 | 国产 欧美一区二区三区四区| 日韩三级人妇| 久久99日韩欧美成人精品| 91熟女大神| 主播日逼片| 熟女国产区二区| 色色综合日韩综合| 欧美黄色三级片大香蕉|