日日操日日操,亚洲日本午夜激情,人妻内射精品一区二区,国产一区北条麻妃

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日本美女内射视频网站,高潮美女操久久
Rabbit Anti-LRSAM1/Cy5.5 Conjugated antibody (bs-9387R-Cy5.5)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-9387R-Cy5.5
英文名稱 Rabbit Anti-LRSAM1/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標(biāo)記的LRSAM1蛋白抗體
別    名 E3 ubiquitin protein ligase LRSAM1; hTAL; Leucine rich repeat and sterile alpha motif containing protein 1; RIFLE; TAL; Tsg101 associated ligase; LRSM1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞粘附分子  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 84kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LRSAM1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
LRSAM1 is an E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivation of the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos. It selectively regulates cell adhesion molecules and plays a role in receptor endocytosis and viral budding. LRSAM1 contains a RING-type zinc finger, 5 leucine-rich repeats and 1 SAM (sterile alpha motif) domain. The coiled coil domains interact with the SB domain of TSG101. The PTAP motifs mediate the binding to UEV domains. There are 3 isoforms produced by alternative splicing.

Function:
E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos.

Subunit:
Interacts with TSG101.

Subcellular Location:
Cytoplasm. Note=Displays a punctuate distribution and localizes to a submembranal ring.

Tissue Specificity:
Highly expressed in adult spinal cord motoneurons as well as in fetal spinal cord and muscle tissue.

DISEASE:
Defects in LRSAM1 are a cause of Charcot-Marie-Tooth disease type 2P (CMT2P) [MIM:614436]. CMT2P is an axonal form of Charcot-Marie-Tooth disease, a disorder of the peripheral nervous system, characterized by progressive weakness and atrophy, initially of the peroneal muscles and later of the distal muscles of the arms. Charcot-Marie-Tooth disease is classified in two main groups on the basis of electrophysiologic properties and histopathology: primary peripheral demyelinating neuropathies (designated CMT1 when they are dominantly inherited) and primary peripheral axonal neuropathies (CMT2). Neuropathies of the CMT2 group are characterized by signs of axonal degeneration in the absence of obvious myelin alterations, normal or slightly reduced nerve conduction velocities, and progressive distal muscle weakness and atrophy. Nerve conduction velocities are normal or slightly reduced.

Similarity:
Contains 6 LRR (leucine-rich) repeats.
Contains 1 RING-type zinc finger.
Contains 1 SAM (sterile alpha motif) domain.

Database links:

Entrez Gene: 90678 Human

Omim: 610933 Human

SwissProt: Q6UWE0 Human

Unigene: 495188 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 m.bklrv.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
凹凸自拍偷拍视频自拍偷拍熟女视频 | 国产精品久久99 香蕉视频| 欧美 国产 日韩精品| 人妻在线x爱| 日韩欧美大片一区| 野狼社区中文深夜99爽| 日韩欧美高清精品一区| 久久精品高潮喷水| 四虎髙清成人永久性视频| 国产精品人与拘| 亚洲久久久久久久9999| 852一区二三区网站| 葵司在线日韩精品一区二| 久久久精品黄网站| 日韩超清一区| 久久九九精品视频网bl| 免费在线草| 色婷婷久久久精品| 操逼啊啊啊好爽大鸡巴操逼一级片| 成年人又黄又爽又色| 国产精品美女自拍偷拍| 蜜桃免费观看网站操鸡| 免费91成人黄色比| 国产欧美日韩操| 99久久久人妻| 黄色国产录像| 这里只有精品蜜臀| 色小说在线免费观看| 欧美又粗又大一区二区在线| 国产在线91视频| 色播人人妻人人色| 欧美 日韩 国产 亚洲 .com| 中国亚洲D级视频网站| 亚洲丰满熟妇熟女一区二区| 噜噜噜噜噜噜久久久久久久久久| 好吊妞视频好吊妞| 亚洲成人午夜福利在线| 日韩高清无码视屏| 国产亚洲日本韩国| 1024香蕉av| 射呦呦|