日日操日日操,亚洲日本午夜激情,人妻内射精品一区二区,国产一区北条麻妃

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
91人妻人人澡人人爽人人DVD,亚洲惰色丁香久久
Rabbit Anti-LRSAM1/BF647 Conjugated antibody (bs-9387R-BF647)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-9387R-BF647
英文名稱 Rabbit Anti-LRSAM1/BF647 Conjugated antibody
中文名稱 BF647標(biāo)記的LRSAM1蛋白抗體
別    名 E3 ubiquitin protein ligase LRSAM1; hTAL; Leucine rich repeat and sterile alpha motif containing protein 1; RIFLE; TAL; Tsg101 associated ligase; LRSM1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 84kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LRSAM1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
LRSAM1 is an E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivation of the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos. It selectively regulates cell adhesion molecules and plays a role in receptor endocytosis and viral budding. LRSAM1 contains a RING-type zinc finger, 5 leucine-rich repeats and 1 SAM (sterile alpha motif) domain. The coiled coil domains interact with the SB domain of TSG101. The PTAP motifs mediate the binding to UEV domains. There are 3 isoforms produced by alternative splicing.

Function:
E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos.

Subunit:
Interacts with TSG101.

Subcellular Location:
Cytoplasm. Note=Displays a punctuate distribution and localizes to a submembranal ring.

Tissue Specificity:
Highly expressed in adult spinal cord motoneurons as well as in fetal spinal cord and muscle tissue.

DISEASE:
Defects in LRSAM1 are a cause of Charcot-Marie-Tooth disease type 2P (CMT2P) [MIM:614436]. CMT2P is an axonal form of Charcot-Marie-Tooth disease, a disorder of the peripheral nervous system, characterized by progressive weakness and atrophy, initially of the peroneal muscles and later of the distal muscles of the arms. Charcot-Marie-Tooth disease is classified in two main groups on the basis of electrophysiologic properties and histopathology: primary peripheral demyelinating neuropathies (designated CMT1 when they are dominantly inherited) and primary peripheral axonal neuropathies (CMT2). Neuropathies of the CMT2 group are characterized by signs of axonal degeneration in the absence of obvious myelin alterations, normal or slightly reduced nerve conduction velocities, and progressive distal muscle weakness and atrophy. Nerve conduction velocities are normal or slightly reduced.

Similarity:
Contains 6 LRR (leucine-rich) repeats.
Contains 1 RING-type zinc finger.
Contains 1 SAM (sterile alpha motif) domain.

Database links:

Entrez Gene: 90678 Human

Omim: 610933 Human

SwissProt: Q6UWE0 Human

Unigene: 495188 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 m.bklrv.cn 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
嗯嗯嗯不要嗯嗯视频| www欧美人妻少妇一区二区三区| 又粗又大又猛的视频| 日本视频免费试看1分钟| 日韩3p大乱交| 91国精品产品 区二区三区蜜臀| 国产福利院一区二区| 天天综合性成人网| 久久综合88v一区二区| 9久久品一区国产区成| av在线不卡顿| 激情五月婷婷五月激情| 91从后入直接观看| 九九综合九色综合网站| 精品亚洲国产在| 韩欧美黄片| a人人妻人人澡人人爽久久av| 天天操天天抽天天干| 不卡免费在线看的AV| 久久国产精品99国产精2021| 黑人后入视频在线观看| 亚洲Av片毛片成人观看| 在线网站啪| 岛国不卡视频一区在线播放| 日韩av香蕉在线| AV中国精品一二区| 亚洲图 国产| 日韩欧美中文字幕在线成人| 美女永久在线网站| 操逼动态视频图片| 国产高清激情综合国产在线| 欧美视频精品了| 亚洲精品摄像头| 韩日一区二区三| 隐香淫色天天影视| 日韩无码中字网站| 大鸡巴操BAV| 午夜福利久久久久| 好吊妞无缓冲十一区| 天天日天天爽天天舒服| 国产精品无码a久久久68|