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Rabbit Anti-BCL2L10/BF350 Conjugated antibody (bs-5796R-BF350)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-5796R-BF350
英文名稱 Rabbit Anti-BCL2L10/BF350 Conjugated antibody
中文名稱 BF350標記的BCL2樣10促凋亡蛋白抗體
別    名 Anti apoptotic protein NrH; Anti-apoptotic protein NrH; Apoptosis regulator Bcl B; Apoptosis regulator Bcl-B; B2L10_HUMAN; BCL B; Bcl-2-like protein 10; Bcl2 L 10; BCL2 like 10 (apoptosis facilitator); BCL2 like 10 protein; Bcl2-L-10; Bcl2l10; BCLB; Boo; Diva; MGC129810; MGC129811; Nrh.   
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  細胞凋亡  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit, )
產(chǎn)品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BCL2L10
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. BCL2L10 is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human BCL2L10 protein is widely expressed. Also, the human BCL2L10 functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1.

Function:
Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK.

Subunit:
Binds to Bcl-2, Bcl-X and BAX. Interacts with APAF1.

Subcellular Location:
Mitochondrion. Nucleus membrane.

Tissue Specificity:
Widely expressed in adult tissues.

Similarity:
Belongs to the Bcl-2 family.

Database links:

Entrez Gene: 10017 Human

Omim: 606910 Human

SwissProt: Q9HD36 Human

Unigene: 283672 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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