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Rabbit Anti-SLC14A2/Gold Conjugated antibody (bs-11801R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-11801R-Gold
英文名稱 Rabbit Anti-SLC14A2/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的尿素轉(zhuǎn)運(yùn)型糖蛋白A2抗體
別    名 UT-A; HUT2; kidney; MGC119566; MGC119567; Slc14a2; Solute carrier family 14 (urea transporter), member 2; Solute carrier family 14 member 2; Urea transporter 2; Urea transporter; Urea transporter, kidney; UT-A2; UT2; UT2_HUMAN; UTA; UTR; FLJ16167; hUT-A6.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  通道蛋白  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 101kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC14A2/UT-A
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011]

Function:
Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism.

Subunit:
Isoform 1 interacts with SNAPIN which may be important for recruitment to the plasma membrane.

Subcellular Location:
Apical cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Isoform 1 and isoform 2 are expressed in the inner medulla of the kidney.

Similarity:
Belongs to the urea transporter family.

Database links:

Entrez Gene: 8170 Human

Entrez Gene: 27411 Mouse

Entrez Gene: 54302 Rat

Omim: 601611 Human

SwissProt: Q15849 Human

SwissProt: Q8R4T9 Mouse

SwissProt: Q62668 Rat

Unigene: 710927 Human

Unigene: 44158 Mouse

Unigene: 10157 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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