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Rabbit Anti-5HT6 Receptor/BF488 Conjugated antibody (bs-12058R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-12058R-BF488
英文名稱 Rabbit Anti-5HT6 Receptor/BF488 Conjugated antibody
中文名稱 BF488標記的5-羥色胺受體6抗體
別    名 SR-6; 5 HT 6; 5 HT6; 5 hydroxytryptamine 6 receptor; 5 hydroxytryptamine receptor 6; 5-HT-6; 5-HT6; 5-hydroxytryptamine receptor 6; 5HT 6; 5HT6R_HUMAN; HTR 6; HTR6; Serotonin receptor 6.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 神經(jīng)生物學  細胞膜受體  G蛋白偶聯(lián)受體  新陳代謝  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Horse, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human 5HT6 Receptor/SR-6
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor. [provided by RefSeq, Aug 2013]

Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in several human brain regions, most prominently in the caudate nucleus.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 3362 Human

Entrez Gene: 15565 Mouse

Entrez Gene: 64354 Rat

Omim: 601109 Human

SwissProt: P50406 Human

SwissProt: Q9R1C8 Mouse

SwissProt: P31388 Rat

Unigene: 22180 Human

Unigene: 291096 Mouse

Unigene: 10552 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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