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Rabbit Anti-DDX60/FITC Conjugated antibody (bs-14253R-FITC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價

產(chǎn)品編號 bs-14253R-FITC
英文名稱 Rabbit Anti-DDX60/FITC Conjugated antibody
中文名稱 FITC標記的ATP依賴RNA解旋酶DDX60抗體
別    名 DDX60; DDX60_HUMAN; DEAD (Asp-Glu-Ala-Asp) box polypeptide 60; DEAD box protein 60; Probable ATP-dependent RNA helicase DDX60.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經(jīng)生物學  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, )
產(chǎn)品應用 Flow-Cyt=3ug/Test ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 198kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DDX60
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
DDX60 is a 1,712 amino acid protein belonging to the helicase family. DDX60 contains one helicase ATP-binding domain and one helicase C-terminal domain. The gene encoding DDX60 maps to human chromosome 4, which represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntington gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes.

Similarity:
Belongs to the helicase family.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.

Database links:

Entrez Gene: 55601 Human

Entrez Gene: 234311 Mouse

Entrez Gene: 100360801 Rat

Omim: 613974 Human

SwissProt: Q8IY21 Human

Unigene: 591710 Human

Unigene: 275233 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品圖片
Blank control (Black line): HUVEC (Black). Primary Antibody (green line): Rabbit Anti-DDX60 antibody (bs-14253R-FITC) Dilution: 1μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG-FITC . Protocol The cells were fixed with 4% PFA (10min at room temperature)and then permeabilized with PBST for 20 min at room temperature. The cells then were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. Acquisition of 20,000 events was performed.
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