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Rabbit Anti-CTDSP2/Gold Conjugated antibody (bs-14099R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-14099R-Gold
英文名稱 Rabbit Anti-CTDSP2/Gold Conjugated antibody
中文名稱 膠體金標記的羧基端小結(jié)構(gòu)域磷酸酶2抗體
別    名 Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 2; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; CTDS2_HUMAN; Ctdsp2; NIF2; NLI interacting factor 2; NLI-interacting factor 2; Nuclear LIM interactor interacting factor 2; Nuclear LIM interactor-interacting factor 2; OS4; Protein OS 4; Protein OS-4; PSR2; SCP2; Small C-terminal domain phosphatase 2; Small CTD phosphatase 2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  細胞生物  染色質(zhì)和核信號  信號轉(zhuǎn)導  腫瘤細胞生物標志物  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CTDSP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 Function:
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.

Subunit:
Monomer (By similarity). Interacts with REST.

Subcellular Location:
Nucleus (By similarity).

Tissue Specificity:
Expression is restricted to non-neuronal tissues. Highest expression in pancreas and lowest in liver.

Similarity:
Contains 1 FCP1 homology domain.

Database links:

Entrez Gene: 10106 Human

Entrez Gene: 506115 Cow

Entrez Gene: 52468 Mouse

Omim: 608711 Human

SwissProt: O14595 Human

SwissProt: Q8BX07 Mouse

Unigene: 524530 Human

Unigene: 29490 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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