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Rabbit Anti-FPGS/BF647 Conjugated antibody (bs-13196R-BF647)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-13196R-BF647
英文名稱(chēng) Rabbit Anti-FPGS/BF647 Conjugated antibody
中文名稱(chēng) BF647標(biāo)記的葉酸鹽多谷氨酸合成酶抗體
別    名 EC 6.3.2.17; FOLC; FOLC_HUMAN; Folylpoly gamma glutamate synthetase; Folylpoly-gamma-glutamate synthetase; Folylpolyglutamate synthase; Folylpolyglutamate synthase mitochondrial; FPGS; mitochondrial; OTTHUMP00000022201; OTTHUMP00000022202; Tetrahydrofolate synthase; Tetrahydrofolylpolyglutamate synthase.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  新陳代謝  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FPGS/Folylpolyglutamate synthase
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms. [provided by RefSeq, Jul 2008].

Function:
Conversion of folates to polyglutamate derivatives. This allows tissues to concentrate folate at higher levels than in plasma.

Subunit:
Monomer.

Subcellular Location:
Mitochondrion. Cytoplasm.

Similarity:
Belongs to the folylpolyglutamate synthase family.

Database links:

Entrez Gene: 2356 Human

Omim: 136510 Human

SwissProt: Q05932 Human

Unigene: 335084 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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