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產(chǎn)品中心-北京博奧森生物技術(shù)有限公司
Rabbit Anti-GLYCTK/Gold Conjugated antibody (bs-13448R-Gold)
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說(shuō) 明 書(shū): 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-13448R-Gold
英文名稱1 Rabbit Anti-GLYCTK/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的HBeAg結(jié)合蛋白4/甘油激酶抗體
別    名 HBEBP2; CG9886 like; GLCTK_HUMAN; Glycerate kinase; Glyctk; GLYCTK; HBeAg binding protein 2; HBeAg binding protein 4; HBeAg-binding protein 4; HBeAgBP4A; HBEBP2; HBEBP4.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  細(xì)菌及病毒  新陳代謝  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HBEBP2/GLYCTK
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This locus encodes a member of the glycerate kinase type-2 family. The encoded enzyme catalyzes the phosphorylation of (R)-glycerate and may be involved in serine degradation and fructose metabolism. Decreased activity of the encoded enzyme may be associated with the disease D-glyceric aciduria. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]

Subcellular Location:
Cytoplasm and Cytoplasm. Mitochondrion.

Tissue Specificity:
Widely expressed.

DISEASE:
Defects in GLYCTK are the cause of D-glyceric aciduria (D-GA) [MIM:220120]. D-GA is a rare metabolic disease characterized by chronic metabolic acidosis and a highly variable clinical phenotype. Clinical features range from an encephalopathic presentation with seizures, microcephaly, severe mental retardation and early death, to milder manifestations with only speech delay or even normal development.

Similarity:
Belongs to the glycerate kinase type-2 family.

Database links:

Entrez Gene: 132158 Human

Entrez Gene: 235582 Mouse

Entrez Gene: 684314 Rat

Omim: 610516 Human

SwissProt: Q9BE01 Cynomolgus Monkey

SwissProt: Q8IVS8 Human

SwissProt: Q8QZY2 Mouse

SwissProt: Q0VGK3 Rat

Unigene: 415312 Human

Unigene: 335420 Mouse

Unigene: 202605 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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