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產(chǎn)品中心-北京博奧森生物技術(shù)有限公司
Rabbit Anti-IFI44L/Gold Conjugated antibody (bs-15551R-Gold)
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說(shuō) 明 書(shū): 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-15551R-Gold
英文名稱(chēng)1 Rabbit Anti-IFI44L/Gold Conjugated antibody
中文名稱(chēng) 膠體金標(biāo)記的干擾素誘導(dǎo)蛋白44樣蛋白抗體
別    名 C1orf29; GS3686; IF44L_HUMAN; IFI44L; Interferon-induced protein 44-like.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  微生物學(xué)  細(xì)胞因子  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IFI44L
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
IFI-44L is a 452 amino acid cytoplasmic protein that shares some sequence similarities with IFI-44. IFI-44 is a cytoplasmic protein that aggregates to form microtubule structures. The genes that encode IFI-44L and IFI-44 are located on chromosome 1, which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Function:
Exhibits a low antiviral activity against hepatitis C virus.

Subcellular Location:
Cytoplasm (Potential).

Similarity:
Belongs to the IFI44 family.

Database links:

Entrez Gene: 10964 Human

Omim: 613975 Human

SwissProt: Q53G44 Human

Unigene: 731680 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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