日日操日日操,亚洲日本午夜激情,人妻内射精品一区二区,国产一区北条麻妃

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
色婷婷五月天久久久老色批,好吊操好妞
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-CLCNKB/Cy5 Conjugated antibody (bs-13627R-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13627R-Cy5
英文名稱 Rabbit Anti-CLCNKB/Cy5 Conjugated antibody
中文名稱 Cy5標記的氯離子通道KB抗體
別    名 Bartter syndrome type 3; Chloride channel Kb; Chloride channel kidney B; Chloride channel protein ClC-Kb; Chloride channel voltage sensitive Kb; ClC K2; ClC-K2; ClCK2; CLCKB; CLCKB_HUMAN; CLCNKB; hClC Kb; hClCKb; MGC24087; OTTHUMP00000011120; OTTHUMP00000011121; RP11 5P18.8.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  神經生物學  信號轉導  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 75kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CLCNKB
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport, and maintain cellular volume. CLC-KA is a kidney-specific chloride channel that mediates transepithelial chloride transport in the thin ascending limb of the Henle loop in the inner medulla. CLC-KA plays a crucial role in urine concentration. The gene encoding human CLC-KA maps to chromosome 1p36. Mutations in this gene may be associated with nephrogenic diabetes insipidus in those cases where mutations in the vasopressin V2 receptor and the AQP2 water channel are lacking. CLC-KB mediates basolateral chloride ion efflux in the thick ascending limb and in more distal nephron segments. The gene encoding human CLC-KB maps to chromosome 1p36. Mutations in this gene cause type III Barter’s syndrome which is characterized by renal salt-wasting and low blood pressure.

Function:
Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed predominantly in the kidney.

DISEASE:
Defects in CLCNKB are the cause of Bartter syndrome type 3 (BS3) [MIM:607364]; also known as classic Bartter syndrome. It is an autosomal recessive form of often severe intravascular volume depletion due to renal salt-wasting associated with low blood pressure, hypokalemic alkalosis, hypercalciuria, and normal serum magnesium levels.
Defects in CLCNKB are a cause of Bartter syndrome type 4B (BS4B) [MIM:613090]. A digenic, recessive disorder characterized by impaired salt reabsorption in the thick ascending loop of Henle with pronounced salt wasting, hypokalemic metabolic alkalosis, and varying degrees of hypercalciuria. Bartter syndrome type 4B is associated with sensorineural deafness.

Similarity:
Belongs to the chloride channel (TC 2.A.49) family. CLCNKB subfamily.
Contains 2 CBS domains.

Database links:

Entrez Gene: 1188 Human

Entrez Gene: 56365 Mouse

Entrez Gene: 79430 Rat

Omim: 602023 Human

SwissProt: P51801 Human

SwissProt: Q9WUB6 Mouse

SwissProt: P51802 Rat

Unigene: 352243 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 m.bklrv.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
欧美日韩国产亚洲一区| 日韩欧美激情小说图片| 内射美女骚逼特写| 久久久久主播porn| 午夜二区三区| 大香蕉在线八| 午夜福利欧美在线观看视频| 美女一二三区久久久免费看| 亚洲日韩欧美一二三区无码| 6q精品一区二区| 美女大骚逼白虎开房被操国产| 欧洲精品一区二区人妻| 看黄色熟女| 亚洲模特久久久久久久久久| 亚州视频a| 无码中字人妻老牛| av亚洲精品一区二区三区| 国产白丝123区| 少妇久久一起草综合网| 艹逼在线观看网站| 黄色成人美女网站| 免费观看日B视频3.3.0| 九九热成人免费在线视频| 91精品欧美一区二区综合| 日逼逼视频免费网站吗| 粉嫰av午夜| 久久久999区二区三区| 台湾中文娱乐婷婷| 99久久伦理视频| 日韩无码久久免费激情片| 歐美日韓性生活視頻免費觀看網頁 | 操我小骚逼视频| www.av在线| 日韩伦理在线视频7| 三级精品91网址| 午夜AV天堂| 国产极品菊爆掹女高潮| 久久久.ⅴip| 亚洲自拍偷拍区丁香| 91无码视频在线观看网| 亚洲美女偷拍|