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Rabbit Anti-BarX2/BF488 Conjugated antibody (bs-19273R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-19273R-BF488
英文名稱 Rabbit Anti-BarX2/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的BarX2蛋白抗體
別    名 BarH like homeobox 2; BarX 2; BARX homeobox; BARX homeobox 2; Barx2; BARX2_HUMAN; Homeobox protein BarH like 2; Homeobox protein BarH-like 2; MGC133368; MGC133369.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  轉(zhuǎn)錄調(diào)節(jié)因子  細(xì)胞粘附分子  結(jié)合蛋白  細(xì)胞骨架  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, Dog, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BarX2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the homeobox transcription factor family. A highly related protein in mouse has been shown to influence cellular processes that control cell adhesion and remodeling of the actin cytoskeleton in myoblast fusion and chondrogenesis. The encoded protein may also play a role in cancer progression. [provided by RefSeq, Jul 2008]

Function:
Transcription factor. Binds optimally to the DNA consensus sequence 5'-YYTAATGRTTTTY-3'. May control the expression of neural adhesion molecules such as L1 or Ng-CAM during embryonic development of both the central and peripherical nervous system. May be involved in controlling adhesive processes in keratinizing epithelia.

Subcellular Location:
Nucleus.

Tissue Specificity:
Highly expressed in adult salivary gland and at much lower levels in mammary gland, kidney and placenta.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the BAR homeobox family.
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 8538 Human

Entrez Gene: 12023 Mouse

Entrez Gene: 679701 Rat

Omim: 604823 Human

SwissProt: Q9UMQ3 Human

SwissProt: O08686 Mouse

Unigene: 591944 Human

Unigene: 261044 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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