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Rabbit Anti-ZNT6/BF647 Conjugated antibody (bs-16414R-BF647)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-16414R-BF647
英文名稱 Rabbit Anti-ZNT6/BF647 Conjugated antibody
中文名稱 BF647標記的ZNT6蛋白抗體
別    名 FLJ31101; MSTP103; SLC30A6; Solute carrier family 30 (zinc transporter), member 4; Solute carrier family 30 (zinc transporter), member 6; Solute carrier family 30 member 6; Zinc transporter 6; Zinc transporter like 3; ZnT-6; ZnT6; ZNT6_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNT6
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A6, permit cellular efflux of zinc (Seve et al., 2004 [PubMed 15154973]).[supplied by OMIM, Mar 2008]

Function:
Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment.

Subcellular Location:
Golgi apparatus > trans-Golgi network membrane. Found in vesicules.

Tissue Specificity:
Expressed in brain; especially in cerebellum, hippocampus, parahippocampal gyrus, superior and middle temporal gyrus. Also expressed in B cells, colon, eye, and lung. Lower expression was present in bone, brain, cervix, ear, heart, kidney, muscle, nerve, pancreas, prostate, skin, stomach, and testis.

Similarity:
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4)
family. SLC30A subfamily.

Database links:

Entrez Gene: 55676 Human

Entrez Gene: 210148 Mouse

Omim: 611148 Human

SwissProt: Q6NXT4 Human

SwissProt: Q8BJM5 Mouse

Unigene: 23248 Human

Unigene: 243943 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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