日日操日日操,亚洲日本午夜激情,人妻内射精品一区二区,国产一区北条麻妃

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
正在播放后入内射少妇,一區二區女人五十路六十路視頻在線,国产字幕中文久久网
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-IREB2/Cy5.5 Conjugated antibody (bs-4484R-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-4484R-Cy5.5
英文名稱 Rabbit Anti-IREB2/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標記的鐵反應(yīng)元件結(jié)合蛋白2抗體
別    名 IRP 2; IRP-2; IRP2; ACO3; FLJ23381; IRE BP2; IRE-BP 2; IREB 2; IREB2; IREB2_HUMAN; iron regulatory protein 2; iron responsive element binding protein 2; Iron-responsive element-binding protein 2; irp2; IRP2AD; OTTHUMP00000185022.   
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  免疫學  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Rabbit, Caenorhabditis elegans)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 105kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IREB2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
?Iron metabolism is essential for sustaining mammalian homeostasis. Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins: IRP-1 and -2 (iron regulatory protein-1 and -2), also known as iron responsive element-binding protein-1 and -2 (IRE-BP-1 and -2) or aconitase 1 and 2. IRP-1 and IRP-2 are important soluble regulatory factors that mediate iron uptake and storage in mammalian cells. They are capable of either repressing translation or enhancing mRNA stability by associating with stem-loop motifs known as iron-responsive elements (IREs). IRPs respond to stress mediators, iron concentration and signaling factors, including nitrogen monoxide, cytokines and hydrogen peroxide.

Function:
RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

Subcellular Location:
Cytoplasm.

Post-translational modifications:
Ubiquitinated and degraded by the proteasome in presence of high level of iron and oxygen. Ubiquitinated by a SCF complex containing FBXL5. Upon iron and oxygen depletion FBXL5 is degraded, preventing ubiquitination and allowing its RNA-binding activity.

Similarity:
Belongs to the aconitase/IPM isomerase family.

Database links:

Entrez Gene: 3658 Human

Entrez Gene: 475134 Dog

Entrez Gene: 64602 Mouse

Entrez Gene: 100153993 Pig

Entrez Gene: 64831 Rat

Omim: 147582 Human

SwissProt: P48200 Human

SwissProt: Q811J3 Mouse

SwissProt: B3VKQ2 Pig

SwissProt: Q62751 Rat

Unigene: 436031 Human

Unigene: 208991 Mouse

Unigene: 10132 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 m.bklrv.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
美国不卡av在线免费观看| 日本。一区 不卡| 狠狠久久亚洲欧美| 人人操天天操夜夜操b| 人人妻人人干人人看| 黄v在线亚洲| 日韩欧美夫妻精品区| 公开超碰欧美精品| 国产日韩 欧美 在线| 亚洲天堂性| 欧美色爱日韩精品综合| 亚洲AV电影免费看| 亚洲丰满少妇人妻| 97色综合国产亚洲| 亚洲无码视频你懂的| 丁香五月深爱激情| 色逼逼网站| 久久无码懂色| 欧美 bt 日韩| 丁香五月破处啪啪| 明星一区二区三区| 日日干日日操日日射| 久久99精品中文| 国产精品小视频91麻豆| 麻豆专区第一页| 无码av亚洲图片| 欧美成人午夜在线观看| MM青涩在线免费视频| 欧美老女一级特级黄片撒尿特级| AV天天操天天日| 艹B视频在线免费| 红杏一级AV| 精品人妻嫩妻少妇AV| 欧美丝袜综合人妻| 午夜视频18以下不能进二区三区| 久久免费电影无码流出| 精品久久A√| 入妻av电影| 不卡三区ai在线| 又猛又粗又爽的视频| 日韩欧美国产成人一区二区|