日日操日日操,亚洲日本午夜激情,人妻内射精品一区二区,国产一区北条麻妃

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
伊人精品大香蕉婷婷,内射一级内射
Rabbit Anti-IREB2/BF555 Conjugated antibody (bs-4484R-BF555)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-4484R-BF555
英文名稱 Rabbit Anti-IREB2/BF555 Conjugated antibody
中文名稱 BF555標(biāo)記的鐵反應(yīng)元件結(jié)合蛋白2抗體
別    名 IRP 2; IRP-2; IRP2; ACO3; FLJ23381; IRE BP2; IRE-BP 2; IREB 2; IREB2; IREB2_HUMAN; iron regulatory protein 2; iron responsive element binding protein 2; Iron-responsive element-binding protein 2; irp2; IRP2AD; OTTHUMP00000185022.   
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  新陳代謝  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Rabbit, Caenorhabditis elegans)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 105kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IREB2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
?Iron metabolism is essential for sustaining mammalian homeostasis. Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins: IRP-1 and -2 (iron regulatory protein-1 and -2), also known as iron responsive element-binding protein-1 and -2 (IRE-BP-1 and -2) or aconitase 1 and 2. IRP-1 and IRP-2 are important soluble regulatory factors that mediate iron uptake and storage in mammalian cells. They are capable of either repressing translation or enhancing mRNA stability by associating with stem-loop motifs known as iron-responsive elements (IREs). IRPs respond to stress mediators, iron concentration and signaling factors, including nitrogen monoxide, cytokines and hydrogen peroxide.

Function:
RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

Subcellular Location:
Cytoplasm.

Post-translational modifications:
Ubiquitinated and degraded by the proteasome in presence of high level of iron and oxygen. Ubiquitinated by a SCF complex containing FBXL5. Upon iron and oxygen depletion FBXL5 is degraded, preventing ubiquitination and allowing its RNA-binding activity.

Similarity:
Belongs to the aconitase/IPM isomerase family.

Database links:

Entrez Gene: 3658 Human

Entrez Gene: 475134 Dog

Entrez Gene: 64602 Mouse

Entrez Gene: 100153993 Pig

Entrez Gene: 64831 Rat

Omim: 147582 Human

SwissProt: P48200 Human

SwissProt: Q811J3 Mouse

SwissProt: B3VKQ2 Pig

SwissProt: Q62751 Rat

Unigene: 436031 Human

Unigene: 208991 Mouse

Unigene: 10132 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 m.bklrv.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
欧美+日韩+国产性爱在线观看 | 美女密臂AⅤ| 特A特黄日韩欧美在线黄片| 欧洲美女裸交视频在线看| 嗯啊啊,,嗯清晨在厨房后入| 就是干天天射欧美| 日韩大又长又租又大| 人妻交换 在线| 精品不卡av| 欧美同性无码一区二区| 精品乱码一区二区三区免费视频| 日日日插AV| 亚洲精品NV| 国产精品无码流白浆| 欧美激情综合亚洲一二区| 午夜操一操| 欧美久久不卡狠狠久久| 1区二区综合网| 草草影院三区四区| 人妻久久啊啊| 日本色9999| 三级久久三级久久三级久久三级 | 色婷自中文字幕| 国产欧美亚洲777| 日本人天天日日夜夜操一二三道区| cb视频在线观看艹比视频在线观看| 精品176一区二区三区| 久久久亚洲色妇| 少妇被操到喷水| 黄色毛片夫妻免费| 亚洲无码一级免费| 欧美日韩国产综合网站| 少妇AV三区| 无码日韩久久精品国产欧美| 日本有码正在播放| 91久久婷婷人人澡人| 麻豆黄色录像带| 自偷拍免视频| 69视频入| 亚洲 欧美 日韩 最新| 激情五月日韩欧美|