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Rabbit Anti-HSDL1/Gold Conjugated antibody (bs-16553R-Gold)
訂購熱線:400-901-9800
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-16553R-Gold
英文名稱 Rabbit Anti-HSDL1/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的類固醇脫氫酶樣蛋白1抗體
別    名 hsdl1; Hydroxysteroid dehydrogenase like protein 1; HSDL1_HUMAN; steroid dehydrogenase like.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 37kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HSDL1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
HSDL1 is a 330 amino acid protein that belongs to the short-chain dehydrogenases/reductases (SDR) family and 17-beta-HSD 3 subfamily. Localizing to the mitochondrion, HSDL1 is highly expressed in testis and ovary, with lower levels of expression found in thyroid, spinal cord, adrenal gland, heart, placenta, skeletal muscle, small intestine, colon, spleen, prostate and pancreas. HSDL1 interacts with DUSP24 and is encoded by a gene that maps to human chromosome 16q23.3 and mouse chromosome 8 E1. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA, and is associated with a variety of genetic disorders. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16 through the CREBBP gene, which encodes a critical CREB binding protein. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.

Function:
Highly expressed in testis and ovary. Also detected in thyroid, spinal cord, adrenal gland, heart, placenta, skeletal muscle, small intestine, colon, spleen, prostate and pancreas.

Subcellular Location:
Mitochondrion.

Tissue Specificity:
Highly expressed in testis and ovary. Also detected in thyroid, spinal cord, adrenal gland, heart, placenta, skeletal muscle, small intestine, colon, spleen, prostate and pancreas.

Similarity:
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.

Database links:

Entrez Gene: 83693 Human

Entrez Gene: 72552 Mouse

Entrez Gene: 361418 Rat

SwissProt: Q3SXM5 Human

SwissProt: Q8BTX9 Mouse

SwissProt: Q4V8B7 Rat

Unigene: 555992 Human

Unigene: 36756 Mouse

Unigene: 199069 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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