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Rabbit Anti-Trehalase/PE Conjugated antibody (bs-16712R-PE)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-16712R-PE
英文名稱 Rabbit Anti-Trehalase/PE Conjugated antibody
中文名稱 PE標(biāo)記的海藻糖酶抗體
別    名 Alpha alpha trehalase; Alpha alpha trehalose glucohydrolase; Alpha; alpha-trehalase; alpha-trehalose glucohydrolase; Brush border membrane glycoprotein; MGC129621; TRE; TREA; TREA_HUMAN; TREH; Trehalase.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 64kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Trehalase
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Trehalase, also known as TREH, TREA or α,α-trehalose glucohydrolase, is a 583 amino acid protein belonging to the glycosyl hydrolase 37 family. Localizing to cell membrane and lipid-anchor, Trehalase is expressed in kidney, liver, and small intestine. Trehalase hydrolyses ingested trehalose, a disaccharide formed by two glucose molecules found mainly in insects, fungi, and plants, into cellular substrate glucose. Isolated trehalose intolerance due to deficiencies of Trehalase can result in gastrointestinal symptoms. Trehalase may also be a marker for renal tubular damage, and may contain an N-terminal signal peptide, five potential N-glycosylation sites, and a C-terminal hydrophobic region for glycosylphosphatidylinositol (GPI) attachment. Existing as two alternatively spliced isoforms, the gene encoding Trehalase maps to human chromosome 11q23.3.

Function:
Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose.

Subcellular Location:
Cell membrane.

DISEASE:
Note=Deficiency of TREH results in isolated trehalose intolerance that causes gastrointestinal symptoms after ingestion of edible mushrooms.

Similarity:
Sequence similaritiesBelongs to the glycosyl hydrolase 37 family.

Database links:

Entrez Gene: 11181 Human

Omim: 275360 Human

SwissProt: O43280 Human

Unigene: 129712 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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