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Rabbit Anti-KCNH3/BF488 Conjugated antibody (bs-16884R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-16884R-BF488
英文名稱 Rabbit Anti-KCNH3/BF488 Conjugated antibody
中文名稱 BF488標記的KCNH3蛋白抗體
別    名 BEC1; Brain-specific eag-like channel 1; ELK channel 2; ELK2; Ether-a-go-go-like potassium channel 2; Kv12.2; Melk2; Potassium voltage-gated channel, subfamily H (eag-related), member 3; Voltage-gated potassium channel subunit Kv12.2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 117kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNH3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Voltage gated potassium (Kv) channels represent the most complex class of voltage gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNH3 is a pore forming (alpha) subunit of voltage-gated potassium channel. It elicits an outward current with fast inactivation.

Subunit:
The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

Subcellular Location:
Membrane; Multipass membrane protein.

Tissue Specificity:
Detected only in brain, in particular in the telencephalon. Detected in the cerebral cortex, occipital pole, frontal and temporal lobe, putamen, amygdala, hippocampus and caudate nucleus.

Similarity:
Contains 1 cyclic nucleotide-binding domain.
Contains 1 PAC (PAS-associated C-terminal) domain.
Contains 1 PAS (PER-ARNT-SIM) domain.

Database links:

Entrez Gene: 23416 Human

Entrez Gene: 16512 Mouse

Entrez Gene: 27150 Rat

Omim: 604527 Human

SwissProt: Q9ULD8 Human

SwissProt: Q9WVJ0 Mouse

SwissProt: O89047 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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