日日操日日操,亚洲日本午夜激情,人妻内射精品一区二区,国产一区北条麻妃

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
日韩无码免费的,久久艹性视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-phospho-KAT5 (Ser90)/BF555 Conjugated antibody (bs-17097R-BF555)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-17097R-BF555
英文名稱 Rabbit Anti-phospho-KAT5 (Ser90)/BF555 Conjugated antibody
中文名稱 BF555標記的磷酸化組蛋白乙酰轉移酶KAT5抗體
別    名 KAT5 / Tip60 (phospho S90); p-KAT5 / Tip60 (phospho S90); 60 kDa Tat interactive protein; 60 kDa Tat-interactive protein; cPLA(2) interacting protein; cPLA(2)-interacting protein; cPLA2; cPLA2 interacting protein; ESA1; Histone acetyltransferase HTATIP; Histone acetyltransferase KAT5; HIV 1 Tat interactive protein; HIV 1 Tat interactive protein, 60kDa; HIV-1 Tat interactive protein; HTATIP; HTATIP1; K(lysine) acetyltransferase 5; K-acetyltransferase 5; KAT5; KAT5_HUMAN; Lysine acetyltransferase 5; PLIP; Tat interacting protein, 60kDa; TIP; Tip60.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 細胞生物  免疫學  信號轉導  轉錄調節(jié)因子  新陳代謝  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 59kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human KAT5 around the phosphorylation site of Ser90
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Function:
Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation.

Subcellular Location:
Nucleus > nucleolus. Cytoplasm > perinuclear region. Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region and UV irradiation induces translocation into punctuate subnuclear structures named nuclear bodies.

Post-translational modifications:
Sumoylated by UBE2I at Lys-430 and Lys-451, leading to increase of its histone acetyltransferase activity in UV-induced DNA damage response, as well as its translocation to nuclear bodies.
Phosphorylated on Ser-86 and Ser-90; enhanced during G2/M phase.
Phosphorylated form has a higher activity.
Ubiquitinated by MDM2, leading to its proteasome-dependent degradation.

Similarity:
Belongs to the MYST (SAS/MOZ) family.
Contains 1 C2HC-type zinc finger.

Database links:

Entrez Gene: 10524 Human

Entrez Gene: 81601 Mouse

Entrez Gene: 192218 Rat

Omim: 601409 Human

SwissProt: Q92993 Human

SwissProt: Q8CHK4 Mouse

SwissProt: Q99MK2 Rat

Unigene: 397010 Human

Unigene: 228930 Mouse

Unigene: 6629 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 m.bklrv.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
免费久久黄色片| 色999亚洲人成色| 欧美图片精品一区二区| 日本高清不卡在线一区二区| 久久久久日本精品视频| 国产成人夜色高潮褔利在线视频| 色婷婷色一本久久| 成人大香蕉AV| 美女一级视频| 久久尹<| 无码人妻欧美一区二| 日本极品99| 亚洲久久久中文字幕久| 国产又猛又黑又粗又长| 午夜激情91| 国产精品一区久久| 欧美69内射美女| 求网址精品大码在线| 好吊妞公开视频| 日本无码中文字幕第1页| 日韩老熟妇在线| 啊啊啊啊好爽啊啊操我视频| 骚人妻12P| 亚洲A∨无码久久| 同产 欧美 麻豆 精品| 久久久激情影院免费日本| 亚洲品精一区三区三区三区| 艹逼网站在线播放| 欧美日韩在线看片| 日韩一区精品| 精品影院一区| 天天做天天舔天天爽无码| 日韩人妻破解| 日B在线高清| 欧美一级福利频道| 无遮挡网站上| 日韩内射片| 天堂a在线观看99| 国产一区日本一区欧美一区| 亚洲AV人产精品| 偷拍无码人妻|