日日操日日操,亚洲日本午夜激情,人妻内射精品一区二区,国产一区北条麻妃

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
人妻JULiA网址,久久少妇77,欧美精品99久久七区
Rabbit Anti-phospho-KAT5 (Ser90)/PE-Cy7 Conjugated antibody (bs-17097R-PE-Cy7)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-17097R-PE-Cy7
英文名稱 Rabbit Anti-phospho-KAT5 (Ser90)/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標(biāo)記的磷酸化組蛋白乙酰轉(zhuǎn)移酶KAT5抗體
別    名 KAT5 / Tip60 (phospho S90); p-KAT5 / Tip60 (phospho S90); 60 kDa Tat interactive protein; 60 kDa Tat-interactive protein; cPLA(2) interacting protein; cPLA(2)-interacting protein; cPLA2; cPLA2 interacting protein; ESA1; Histone acetyltransferase HTATIP; Histone acetyltransferase KAT5; HIV 1 Tat interactive protein; HIV 1 Tat interactive protein, 60kDa; HIV-1 Tat interactive protein; HTATIP; HTATIP1; K(lysine) acetyltransferase 5; K-acetyltransferase 5; KAT5; KAT5_HUMAN; Lysine acetyltransferase 5; PLIP; Tat interacting protein, 60kDa; TIP; Tip60.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
產(chǎn)品類(lèi)型 磷酸化抗體 
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  新陳代謝  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 59kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human KAT5 around the phosphorylation site of Ser90
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Function:
Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation.

Subcellular Location:
Nucleus > nucleolus. Cytoplasm > perinuclear region. Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region and UV irradiation induces translocation into punctuate subnuclear structures named nuclear bodies.

Post-translational modifications:
Sumoylated by UBE2I at Lys-430 and Lys-451, leading to increase of its histone acetyltransferase activity in UV-induced DNA damage response, as well as its translocation to nuclear bodies.
Phosphorylated on Ser-86 and Ser-90; enhanced during G2/M phase.
Phosphorylated form has a higher activity.
Ubiquitinated by MDM2, leading to its proteasome-dependent degradation.

Similarity:
Belongs to the MYST (SAS/MOZ) family.
Contains 1 C2HC-type zinc finger.

Database links:

Entrez Gene: 10524 Human

Entrez Gene: 81601 Mouse

Entrez Gene: 192218 Rat

Omim: 601409 Human

SwissProt: Q92993 Human

SwissProt: Q8CHK4 Mouse

SwissProt: Q99MK2 Rat

Unigene: 397010 Human

Unigene: 228930 Mouse

Unigene: 6629 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 m.bklrv.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
大香蕉 久久| 欧美一区二区亚洲天堂黑色| 加勒比久在线综合888| 黑人大屌操日本女人B| 精品少妇人妻av一区二区三| 麻豆制作传媒视频在线| www,esag,黄片一1级| 日韩在线干B| 亚洲综合一二三区| 久久久久黄色片网站| 亚洲国产二区| 小色哥资源网一区| 国产 日韩 第一页| 日韩成人AV手机在线看| 最新亚洲精品在线不卡| 午夜最骚18| 久久99中文字幕豆传媒| 玖玖色高清视频在线播放| 韩国av 一区二区| 艾梅柏·希尔德AV网站| 国产精品不卡一区二区久久| 天天干夜夜操夜夜操夜夜摸| 午夜福利久久久久久久久久| 日韩欧一级片| 日韩 欧美 国产二区| 色婷婷久久app| 国产传媒91精品合集| 一区二区伊人91| 国产精亚洲精视频综合区| 三级毛视频| 欧美一级黄片视频在线免费看| 亚洲精品网站 在线播放glf | 中文字库日韩有码| 亚洲一区亚洲二区中文字幕| 又粗又长又免费视频| 亚洲天堂男人天堂中文字幕| 操逼美女操操日| 8840 午夜| 欧美在线 大香蕉| 久久国产高清女同| 国内激情av|