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Rabbit Anti-SBEM/Gold Conjugated antibody (bs-17247R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-17247R-Gold
英文名稱 Rabbit Anti-SBEM/Gold Conjugated antibody
中文名稱 膠體金標記的粘蛋白樣蛋白1抗體
別    名 mucin like 1; mucin-like 1; Mucin-like protein 1; MUCL1; MUCL1_HUMAN; Protein BS106; Small breast epithelial mucin.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  細胞生物  信號轉導  細胞粘附分子  細胞類型標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 7kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SBEM
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
SBEM is a 90 amino acid secreted membrane protein that may play a role as marker for the diagnosis of metastatic breast cancer. SBEM contains three tandem copies of a neutral octapeptide core repeat, and its N- and C-terminal regions are charged and fairly polar. These features are similar to many sialomucins, although the SBEM protein lacks a transmembrane domain and is shorter than most other known epithelial mucins. Expressed in mammary, salivary glands, prostate and also in lung, SBEM is mainly expressed in cancer cell lines of breast origin. SBEM is also highly expressed in lymph node-positive compared with node-negative tumors and in all lymph node containing metastatic cells. The SBEM gene is conserved in chimpanzee, cow, mouse, rat, chicken, zebrafish, C.elegans and M.grisea, and maps to human chromosome 12q13.2.

Function:
May play a role as marker for the diagnosis of metastatic breast cancer.

Subcellular Location:
O-glycosylated.

Tissue Specificity:
Expressed in mammary, salivary glands and prostate. Also detected in lung. Mainly expressed in cancer cell lines of breast origin. Highly expressed in lymph node-positive compared with node-negative tumors. Detected in all lymph node containing metastatic cells.

Post-translational modifications:
O-glycosylated.

Database links:

Entrez Gene: 118430 Human

Omim: 610857 Human

SwissProt: Q96DR8 Human

Unigene: 348419 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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