| 產(chǎn)品編號(hào) | bs-17348R-BF488 |
| 英文名稱 | Rabbit Anti-HOGA1/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的HOGA1蛋白抗體 |
| 別 名 | 4 hydroxy 2 oxoglutarate aldolase 1; C10orf65; DHDPS like protein; DHDPS2; DHDPSL; Dihydrodipicolinate synthase like; Dihydrodipicolinate synthase like, mitochondrial; Dihydrodipicolinate synthetase homolog 2; FLJ37472; HOGA1; HOGA1_HUMAN; HP3; mitochondrial; N acetylneuraminate pyruvate lyase 2 (putative); NPL2; Probable 2 keto 4 hydroxyglutarate aldolase; Probable 4 hydroxy 2 oxoglutarate aldolase mitochondrial; Probable 4-hydroxy-2-oxoglutarate aldolase; Probable KHG aldolase; Protein 569272. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, (predicted: Human, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 32kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HOGA1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: DHDPSL is a 327 amino acid mitochondrial protein that catalyzes the last step in the hydroxyproline metabolic pathway. Existing as two alternatively spliced isoforms, DHDPSL is expressed in kidney and liver and is inhibited by divalent cations. Defects in the gene that encode DHDPSL are the cause of primary hyperoxalurea type III (HP3), a disorder of calcium oxalate nephrolithiasis. Patients with HP3 excrete urine with elevated levels of oxalate and L-glycerate. The DHDPSL gene maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria Database links: Entrez Gene: 112817 Human Entrez Gene: 67432 Mouse Omim: 613597 Human SwissProt: Q86XE5 Human SwissProt: Q9DCU9 Mouse Unigene: 180346 Human Unigene: 24196 Mouse Unigene: 13905 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
