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Rabbit Anti-p21-ARC/BF594 Conjugated antibody (bs-17589R-BF594)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-17589R-BF594
英文名稱(chēng) Rabbit Anti-p21-ARC/BF594 Conjugated antibody
中文名稱(chēng) BF594標(biāo)記的肌動(dòng)蛋白相關(guān)蛋白2/3復(fù)合物亞基3抗體
別    名 Actin related protein 2/3 complex subunit 3; ARC21; ARPC3_HUMAN; ARP2/3 complex 21 kDa subunit; ARP2/3 protein complex subunit p21; ARPC3.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞骨架  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human p21-ARC
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been conserved through evolution and is implicated in the control of actin polymerization in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]

Function:
p21-ARC is part of a complex implicated in the control of actin polymerization in cells. It belongs to a complex composed of ARP2, ARP3, ARPC1, ARPC2, ARPC3, ARPC4 and ARPC5, collectively known as the ARPC3 family. p21-ARC is implicated as an important regulator of growth cone translocation, especially in the CNS (Strasser et al, 2004).

Subunit:
Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and

Subcellular Location:
Cytoplasm, cytoskeleton. Cell projection.

Similarity:
Belongs to the ARPC3 family.

Database links:

Entrez Gene: 10094 Human

Entrez Gene: 56378 Mouse

Entrez Gene: 288669 Rat

Entrez Gene: 415204 Zebrafish

Omim: 604225 Human

SwissProt: O15145 Human

SwissProt: Q9JM76 Mouse

Unigene: 524741 Human

Unigene: 275942 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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