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產(chǎn)品中心-北京博奧森生物技術(shù)有限公司
Rabbit Anti-MON1A/APC Conjugated antibody (bs-17711R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-17711R-APC
英文名稱1 Rabbit Anti-MON1A/APC Conjugated antibody
中文名稱 APC標(biāo)記的MON1A蛋白抗體
別    名 FLJ97088; MGC13272; MON1 homolog A; MON1A; MON1A_HUMAN; SAND1; Vacuolar fusion protein MON1 homolog A.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  轉(zhuǎn)運(yùn)蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Plants, Cynomolgus Monkey)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 62kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MON1A
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
MON1A is a 555 amino acid protein that exists as multiple alternatively spliced isoforms and plays an important role in membrane trafficking, specifically through the secretory apparatus. The gene encoding MON1A maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Function:
Plays an important in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes.

Similarity:
Belongs to the MON1/SAND family.

Database links:

Entrez Gene: 84315 Human

Entrez Gene: 72825 Mouse

Entrez Gene: 315999 Rat

Omim: 611464 Human

SwissProt: Q86VX9 Human

SwissProt: Q6PDG8 Mouse

Unigene: 655014 Human

Unigene: 38037 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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