產(chǎn)品編號 | bs-10782R-Gold |
英文名稱1 | Rabbit Anti-NUP88/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的核孔復(fù)合體蛋白88抗體 |
別 名 | karyoporin; Nuclear pore complex protein 88; Nuclear pore complex protein88; Nucleoporin 88; Nucleoporin 88 kDa; Nucleoporin 88kDa; Nucleoporin88; Nucleoporin88kDa; Nup 84; NUP 88; Nup84; Prei 2; Prei2; Preimplantation protein 2; Preimplantation protein2; NUP88_HUMAN. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 染色質(zhì)和核信號 信號轉(zhuǎn)導(dǎo) 腫瘤細(xì)胞生物標(biāo)志物 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 85kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NUP88 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: NUP88 is a nucleoporin that is an essential component of the nuclear pore complex. It interacts with NUP214/CAN, and is phosphorylated following DNA damage, possibly via the ATM/ATR pathway. NUP88 is also a tumour marker as it is overexpressed in a large number of malignant neoplasms and precancerous dysplasias. Function: Essential component of nuclear pore complex. Subunit: Interacts with NUP214/CAN. Subcellular Location: Nucleus, nuclear pore complex. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Database links: Entrez Gene: 4927 Human Entrez Gene: 19069 Mouse Omim: 602552 Human SwissProt: Q99567 Human SwissProt: Q8CEC0 Mouse Unigene: 584784 Human Unigene: 288962 Mouse Unigene: 11042 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |