日日操日日操,亚洲日本午夜激情,人妻内射精品一区二区,国产一区北条麻妃

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
六月丁香深爱婷婷,国产精选综合一区二区三区
Rabbit Anti-Anillin/BF647 Conjugated antibody (bs-20482R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-20482R-BF647
英文名稱 Rabbit Anti-Anillin/BF647 Conjugated antibody
中文名稱 BF647標(biāo)記的胞環(huán)蛋白肌動蛋白結(jié)合蛋白抗體
別    名 Actin binding protein scraps homolog Drosophila; Actin binding protein anillin; Anillin actin binding protein; ANLN; DKFZp779A055; Scra; Scraps; Scraps homolog.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞周期蛋白  結(jié)合蛋白  細(xì)胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat,  (predicted: Dog, Horse, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 124kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Anillin
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Anillin, also known as scraps homolog, is an evolutionarily conserved Actin- binding protein required for cytokinesis that was first identified in Drosophila melanogaster. Anillin is a ubiquitously expressed protein with highest expression levels in the central nervous system. It is predominantly found in the nucleus and it localizes to the cleavage furrow during cytokinesis, forming a ring with the help of Rac GTPase. During cytokinesis, Anillin interacts with CD2AP and functions to concentrate Rho A and maintain the localization of active Myosin. In Anillin knockout cells the cleavage furrow fails to complete ingression. Anillin expression levels fluctuate with the cell cycle, peaking in mitosis. Before the cell exits into G1, Anillin associates with E-cadherin and is ubiquitinated by the anaphase-promoting complex/cyclosome (APC/C). APC/C recognizes the D-box domain at the N-terminal region of Anillin. Anillin is commonly overexpressed in tumors and may serve as a potential biomarker.Anillin is required for cytokinesis. It is essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression.

Function:
Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression.

Subunit:
Interacts with F-actin. Interacts with CD2AP. May interact with RHOA. Interacts with FZR1/CDH1 during mitotic exit.

Subcellular Location:
Nucleus. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=Mainly found in the nucleus during interphase. Colocalizes with cortical F-actin upon nuclear envelope breakdown in mitosis and subsequently concentrates in the area of the prospective contractile ring in anaphase. This pattern persists until telophase, when the protein becomes concentrated in the midbody.

Tissue Specificity:
Ubiquitously expressed. Present at highest levels in the brain, at high levels in the placenta and testis, at intermediate levels in the intestine, ovary, skeletal muscle and thymus and at lower levels in heart, kidney, liver, lung, pancreas, prostate and spleen. Overexpressed in many tumor types including breast, colorectal, endometrial, hepatic, kidney, lung, ovarian and pancreatic tumors.

Post-translational modifications:
Phosphorylated during mitosis.
Ubiquitinated, and this requires FZR1/CDH1.

Similarity:
Contains 1 PH domain.

Database links:

Entrez Gene: 54443 Human

Entrez Gene: 68743 Mouse

Entrez Gene: 363031 Rat

SwissProt: Q9NQW6 Human

SwissProt: Q8K298 Mouse

Unigene: 62180 Human

Unigene: 282751 Mouse

Unigene: 453238 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 m.bklrv.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
欧美成人日韩在线| 国产精品99久久久久久大便| 日本一道一区二区中文| 国产精品人妻无码久久久使用方法| 美国三级久久久久久久久不能| 中文欧美日b视频| 麻豆69色淫湿| 国产成人一区二无码| 三级片黄蜜臀| 深夜AV在线播放| 台湾精品少妇在线播放| 精品久久久久夜夜夜夜夜| 亚洲av电影网页| 亚洲国产成人在线视频观看 | 人人人妻超碰| 欧美精品人妻六区| 亚洲AV无码AV吞精久久一区| heyzo成人网址| 日不卡久久中文| v综合av| CaoProm在线成人免费| 国产欧美视频一区| 久久i精品ai| 天天B天天日天天干| 刘玥欧美专区视频在线观看| 成人大香蕉av在线播放| 欧美 亚洲 人妻 自拍| 69m.国产福利在线| 干美女官网| 国产中文字幕日本一区| 亚洲图片一区在线| 日本少妇被爽到高潮的动态图| 亚洲香蕉综合一区| 88久久精品99| 日欧美熟妇精品| 国产白丝av动作片| 色欲123区| 大香蕉丁香区| 国产精品高潮露脸二区炮架| 日韩人妻精品欧美| 欧美性感网站免费观看|