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Rabbit Anti-NUP53/AP Conjugated antibody (bs-19546R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-19546R-AP
英文名稱 Rabbit Anti-NUP53/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的核孔復(fù)合蛋白Nup53抗體
別    名 35 kDa nucleoporin; Mitotic phosphoprotein 44; MP 44; MP-44; NP 44; NP44; Nuclear pore complex protein 53kDa; Nuclear pore complex protein Nup 53; Nuclear pore complex protein Nup53; Nuclear pore protein NUP 53; Nuclear pore protein NUP53; Nucleoporin 35kDa; Nucleoporin 53kDa; Nucleoporin Nup 35; Nucleoporin NUP 53; Nucleoporin Nup35; Nucleoporin NUP53; NUP 35; Nup 53; NUP35; NUP53; NUP53_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NUP53
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the nucleoporin family. The encoded protein contains two membrane binding regions, is localized to the nuclear rim, and is part of the nuclear pore complex. All molecules entering or leaving the nucleus either diffuse through or are actively transported by the nuclear pore complex. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 7 and 10. [provided by RefSeq, Dec 2013]

Function:
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs). Can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. May play a role in the association of MAD1 with the NPC.

Subcellular Location:
Nucleus > nuclear pore complex. Nucleus membrane. Tightly associated with the nuclear membrane and lamina.

Similarity:
Belongs to the Nup53 family.
Contains 1 RRM Nup35-type domain.

Database links:

Entrez Gene: 129401 Human

Entrez Gene: 511248 Cow

Entrez Gene: 478830 Dog

Entrez Gene: 100054143 Horse

Entrez Gene: 69482 Mouse

Entrez Gene: 295692 Rat

Entrez Gene: 337461 Zebrafish

Omim: 608140 Human

SwissProt: Q8NFH5 Human

SwissProt: Q8R4R6 Mouse

SwissProt: Q68FY1 Rat

SwissProt: Q6P6X9 Zebrafish

Unigene: 180591 Human

Unigene: 29200 Mouse

Unigene: 203627 Rat

Unigene: 5851 Zebrafish



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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