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Rabbit Anti-Cytohesin 3/Gold Conjugated antibody (bs-20269R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-20269R-Gold
英文名稱 Rabbit Anti-Cytohesin 3/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的胞粘蛋白3抗體
別    名 CYTH3; ARF nucleotide-binding site opener 3; ARNO3; ARNO3 protein; CYH3_HUMAN; Cyth3; Cytohesin-3; General receptor of phosphoinositides 1; Grp1; PH; PH, SEC7 and coiled-coil domain-containing protein 3; Protein ARNO3; PSCD3; SEC7 and coiled-coil domain-containing protein 3; SEC7 homolog C; Sec7-3; Sec7c.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞粘附分子  G蛋白信號(hào)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Cytohesin 3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. [provided by RefSeq, Jul 2008]

Function:
Promotes guanine-nucleotide exchange on ARF1. Promotes the activation of ARF through replacement of GDP with GTP.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Almost absent from liver, thymus and peripheral blood lymphocytes.

Similarity:
Contains 1 PH domain.
Contains 1 SEC7 domain.

Database links:

Entrez Gene: 9265 Human

Entrez Gene: 19159 Mouse

Entrez Gene: 116693 Rat

Omim: 605081 Human

SwissProt: O43739 Human

SwissProt: O08967 Mouse

SwissProt: P97696 Rat

Unigene: 487479 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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