| 產品編號 |
bs-20623R-BF647 |
| 英文名稱 |
Rabbit Anti-N-cadherin/BF647 Conjugated antibody
|
| 中文名稱 |
BF647標記的N-鈣粘附分子抗體 |
| 別 名 |
Cadherin 2; Cadherin 2 N cadherin neuronal; Cadherin 2 type 1; Cadherin 2 type 1 N cadherin neuronal; cadherin 2 type 1 N-cadherin neuronal; Cadherin2; Calcium dependent adhesion protein neuronal; CD325; CD325 antigen; CDH2; CDHN; CDw325; CDw325 antigen; N cadherin 1; NCAD; Neural Cadherin; Neural Cadherin. |
| 規(guī)格價格 |
100ul/2980元
購買 大包裝/詢價 |
| 說 明 書 |
100ul
|
| 研究領域 |
腫瘤 細胞生物 免疫學 激酶和磷酸酶 細胞粘附分子 |
| 抗體來源 |
Rabbit |
| 克隆類型 |
Polyclonal |
| 交叉反應 |
Mouse, Rat,
(predicted: Human, Pig, Cow, Horse, Rabbit, Sheep, )
|
| 產品應用 |
ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
100kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human N-cadherin |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產品介紹 |
background:
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.
Function:
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.
Similarity:
Contains 5 cadherin domains.
Database links:
Entrez Gene: 1000 Human
Entrez Gene: 281062 Cow
Entrez Gene: 12558 Mouse
Entrez Gene: 83501 Rat
Omim: 114020 Human
SwissProt: P19022 Human
SwissProt: P15116 Mouse
SwissProt: Q9Z1Y3 Rat
Unigene: 464829 Human
Unigene: 606106 Human
Unigene: 257437 Mouse
Unigene: 23200 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
細胞粘附蛋白（Call Adhesion Protein）
N-鈣粘附分子屬于依賴鈣離子的細胞間糖蛋白粘附分子的一部分,主要是參與細胞間同源性粘附,調控和介導細胞間相互反應。
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