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產(chǎn)品中心-北京博奧森生物技術(shù)有限公司
Rabbit Anti-AKAP14/HRP Conjugated antibody (bs-23424R-HRP)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-23424R-HRP
英文名稱(chēng)1 Rabbit Anti-AKAP14/HRP Conjugated antibody
中文名稱(chēng) 辣根過(guò)氧化物酶標(biāo)記的A激酶錨定蛋白14抗體
別    名 A kinase (PRKA) anchor protein 14; A kinase anchor protein 14; PRKA14; AKAP-14; AKA14_RAT; Protein kinase A-anchoring protein 14; Protein kinase A anchoring protein 14. TAKAP-1.2; Testis-specific A-kinase-anchoring protein TAKAP-80.   
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 信號(hào)轉(zhuǎn)導(dǎo)  激酶和磷酸酶  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Mouse, Rat, )
產(chǎn)品應(yīng)用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from rat AKAP14
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Constituents: 0.01M PBS, pH 7.4 with 10 mg/mL BSA and 0.1% Gentamicin, 50% glycerol. Or Lyophilized. Buffer = 0.01M PBS, pH 7.4 with 10 mg/mL BSA and 0.1% Gentamicin. Reconstitute with sterile distilled water.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of A-kinase anchoring proteins (AKAPs), a family of functionally related proteins that target protein kinase A to discrete locations within the cell. The human ortholog of this gene has been characterized. It is reported to be enriched in airway cilia and to regulate ciliary beat frequency by anchoring the protein kinase A holoenzyme near substrates in the axoneme. [provided by RefSeq, May 2013].

Function:
Binds to type II regulatory subunits of protein kinase A and anchors/targets them.

Subunit:
Binds to type II regulatory subunits (RII).

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Present in cilia (at protein level). Expressed in tissues containing axoneme-based organelles (cilia and/or flagella): trachea and testis. Highly expressed in airway cilia.

Database links:

Entrez Gene: 434756 Mouse

Entrez Gene: 60332 Rat

SwissProt: O35817 Rat

Unigene: 471848 Mouse

Unigene: 42933 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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